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Additional candidate GSTP1 biomarkers have recently identified in studies describing an inverse association between GSTP1 expression, chemosensitivity and expression of the regulatory microRNA miR-513a-3p in cisplatin-resistant A549 lung cancer cells (Zhang et al, 2012)

2021 Jun;46(4):636-640

Moreover, Study conducted on mouse model reported that LPS can downregulate occluding (a protein in tight junction) in the intestinal epithelial cells and upregulate TNF-, which promotes the expression of -synuclein ( Several research studies suggested that altered GM plays a crucial role in accelerating oxidative stress, inflammation and DNA damage

Without human trial data, clinicians and patients are making decisions based on incomplete information, and the self-reported adverse effect profile anxiety, palpitations, insomnia, fatigue is not benign enough to ignore

Plasma glial fibrillary acidic protein is associated with 18F-SMBT-1 PET: two putative astrocyte reactivity biomarkers for Alzheimers disease

These may interact with proteins, lipids, and DNA to cause protein inactivity, lipid oxidation, and damage to DNA in a chain reaction, which results in a wide range of disease conditions [75,76]