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Materials and methods Animals The study employed adult female SpragueDawley rats, totaling 30 individuals, with each experimental group comprising 6 rats

10.1016/j.jss.2014.10.019 129 KattaS.SrivastavaA.ThangapazhamR

The NFT concentrations observed in the in vitro experiments for glutathione stimulation in this study can hence be considered to be representative or at least close of the concentrations that could be expected in vivo

Secondly, non-chemical stressors (e.g., socioeconomic factors, circadian disruption) are rarely integrated as factors in the research studies even though they modulate CYP activity through inflammatory pathways like IL-6-mediated CYP1A2 suppression (Wang et al., 2022)

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Lacroix M, Beauchemin H, Khandanpour C, Mry T