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Collectively, these data demonstrated multilevel impairment in the metabolism of FA in kidneys of cKOt mice

MOTS-c handles cellular energy regulation, metabolic flexibility, and mitochondrial signaling
Drugs Context 11:114 Niazi S, Gheisari M, Moravvej H, Doroodgar F, Niazi F (2022) Efficacy of cysteamine and methimazole in treating melasma: a comparative narrative review

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This complexity suggests that a more granular analysis at the species or strain level is necessary, as supported by a recent study that individually phenotyped mice colonized with one of the four most represented individual Bacteroides species identified in the microbiome of a 40-strong medicine-free MDD patient versus control cohort

Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation
