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However, despite many hypotheses (558,559) , the only example of ERG acting as a cofactor known to date is an involvement in the biosynthesis of lincomycin (560,561)

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For example, a double-blinded, placebo-controlled trial investigating oral resveratrol supplementation in patients with acute ischemic stroke failed to demonstrate significant improvements in neurological function, as measured by NIHSS, modified Rankin Scale (mRS), or Barthel Index scores at follow-up

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