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In addition to attacking tumor cells, NK cells also enhance the killing ability of T cells by releasing cytokines such as IFN- (72, 73)
Considering previous work showing that the ratio of [1- 13 C]glycine to total HP signal (-glutamyl-[1- 13 C]glycine plus [1- 13 C]glycine) is positively correlated with GGT activity 31 , previous studies showing higher levels of GGT in U87 glioma cells compare to normal brain 19 , and our observation that higher HP [1- 13 C]glycine production in tumor was associated with higher GGT expression in tumor tissue, our results collectively point to the potential of -glutamyl-[1- 13 C]glycine as a HP probe to detect brain tumor in vivo in real time
When glucose starvation occurs, a large amount of NADPH is consumed, and the NADP+/NADPH ratio significantly increases
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Histone modifications mediated by curcumin are not well defined except its function in acetylation, and thus require further investigations to provide insights into its potential mechanism of action
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