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Furthermore, hierarchical clustering was applied to group genes based on their fragments per kilobase of transcript per million mapped reads (FPKM) values

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To evaluate the therapeutic efficacy of DN203316, a novel selective PPAR agonist, HCHF-induced MASH model mice received an intraperitoneal injection at a dose of 3 mg/kg body weight (once daily from week 9 to week 14)