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Consequently, this phenomenon could explain the detection of the nuclear protein HMGB1, a prototypical damage-associated molecular pattern (DAMP) molecule with a proinflammatory function released by both ferroptotic cells and astrocytes, which triggers different immune responses 40

The same mechanisms that help heal tissue could theoretically support tumor blood supply

This step is crucial to prevent the co-separation of free drug with liposomes or the premature leakage of entrapped drug, which are common sources of error in determining encapsulation efficiency of liposomes