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Long-term use of metformin and its effect on serum vitamin B12 with its oral manifestations: a review

Funding: This work was supported in part by the Ontario College of Pharmacists through funding in support of the Pharmacy5in5 program

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Vegetarians and vegans : B12 is found predominantly in animal products, so individuals following plant-based diets may be at risk of deficiency

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Probably, and the prescriber should be testing B12 periodically