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ML162, which is selectively lethal to mutant RAS oncogene-expressing cells (with IC50s of 25 and 578 nM for HRAS G12V -expressing and wild-type RAS-expressing BJeHLT cells, respectively), is another GPX4 inhibitor to suppress tumor cell proliferation [197]

In mice subjected to a methionine-choline-deficient diet, vitamin E antioxidant therapy restored GSH levels (Phung et al

Mechanistic investigations of lipoic acid biosynthesis in Escherichia coli: Both sulfur atoms in lipoic acid are contributed by the same lipoyl synthase polypeptide

It compromises testicular antioxidant capacity and promotes germ cell apoptosis, leading to reduced testosterone levels

Diagnostic and Therapeutic Perspectives Associated to Cobalamin-Dependent Metabolism and Transcobalamins Synthesis in Solid Cancers

Hormonal factors can make fat loss slower in women.