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Drug synergism was measured using the Loewe model with Combenefit software (Cancer Research UK Cambridge Institute), and the combination index was calculated using CompuSyn software (ComboSyn) ( 3 Results 3.1 CB-839 treatment inhibits glutathione synthesis and the conversion of glutamine to glutamate in CLL cell lines Initially, we investigated CB-839s functional inhibition of GLS-1 ( Figures 1A, B )

doi: 10.1515/dmpt-2019-0004, 136

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Cardiovascular support: Research suggests TB-500 may support cardiac tissue repair following ischemic events, with studies showing improved outcomes in animal models of heart damage

Orozco, J