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suffering from any condition that requires treatment with vitamin B 12 such as pernicious anaemia and strict vegans

Studies in rats and beagle dogs have shown a rapid elimination half-life of less than 30 minutes after intravenous administration

As a follow-up, an FDA roadmap has been published, stating that in 35 years time human-relevant testing methods (non-animal New Approach Methods) will be the default for safety/toxicity testing instead of animal studies (218)

Current Research Areas Current literature and supplier documentation are reviewed in the context of compound identity, lot consistency, assay suitability, and controlled research workflow design

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