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However, it had similar temporal pattern, and this activation was prevented by K252a kinase inhibitor and corresponding MEK1 and PI3 kinase inhibitors (PD98059 and LY294002 respectively)

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Pflugers Arch 442:28696 Sato H, Shiiya A, Kimata M, Maebara K, Tamba M, Sakakura Y, Makino N, Sugiyama F, Yagami K, Moriguchi T, Takahashi S, Bannai S (2005) Redox imbalance in cystine/glutamate transporter-deficient mice