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Paracetamol readily crosses the placenta, achieving fetal plasma concentrations similar to maternal levels within a short time after dosing, which ensures direct exposure of the developing brain to parent drug and metabolites (Conings et al., 2019[22]
10.1056/NEJMcibr2013250 [DOI] [PubMed] [Google Scholar] 142.De Jong WH and Borm PJ (2008) Drug delivery and nanoparticles: applications and hazards
Comprehensive analysis of GABA(A)-A1R developmental alterations in rett syndrome: setting the focus for therapeutic targets in the time frame of the disease
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