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References Bayot ML, Moore N, Brannan JM, et al

CrAT has mainly been studied for its role in mitochondrial metabolism, including fatty acid oxidation and acetyl-CoA buffering 3335,44

World gastroenterology organisation global guidelines

Micronized creatine monohydrate is a form of creatine that has been processed to make it smaller and more soluble

This is due to the mechanism that glycogen intermediates are used for triglyceride synthesis and increased levels of triglycerides can cause decreased gallbladder motility and impaired contractility due to sensitivity to cholecystokinin[3,11]

[55], showed that rats, orally receiving radiolabeled LC, metabolized it to -butyrobetaine (up to 31% of the administered dose, present primary in feces) and TMAO (up to 23% of the administered dose, present primary in urine)