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As an antioxidant, glutathione helps neutralize free radicals and reduce oxidative stress that can damage the bodys cells
While traditional paradigms have centered on erythropoietin deficiency and iron dysregulation, it is now evident that accelerated erythrocyte deathdriven by uremic toxins, oxidative stress, chronic inflammation, and iron imbalanceplays a critical role in reducing red blood cell lifespan and exacerbating anemia
Counteracted/attenuated were neuroleptics (i.e., catalepsy) [68,70], L-arginine (i.e., prolonged miosis) [86], N(G)-nitro-L-arginine methyl ester (L-NAME) (prolonged miosis, catalepsy) [70,86], and alcohol acute and chronic intoxication [63,64]
[DOI] [PMC free article] [PubMed] [Google Scholar] 91.De Palma M., Venneri M.A., Galli R., Sergi Sergi L., Politi L.S., Sampaolesi M., Naldini L
Meregalli et al., 2014
Guide to drug porphyrogenicity prediction and drug prescription in the acute porphyrias
