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Cardiovascular Evidence: SELECT Trial Beyond weight loss, semaglutide demonstrated direct cardiovascular protection in the SELECT trial the largest cardiovascular outcomes trial ever conducted in an obesity population

[DOI] [PubMed] [Google Scholar] 59.Antoniades C., Shirodaria C., Warrick N., Cai S., de Bono J., Lee J., Leeson P., Neubauer S., Ratnatunga C., Pillai R., et al

When levels are low, your body struggles to keep up, leaving you tired and sluggish

Patients in their 30s, 40s, and 50s who have maintained training intensity but notice slower recovery, reduced lean mass, and more difficult fat loss are the population that responds most predictably to GH secretagogue therapy

One trial included healthy non-obese participants, demonstrating that the favorable safety profile was not unique to obese individuals

Many drugs used to treat obesity in the past have been discontinued because of their potential to be abused and their toxicities [20-27] (Table 1 )