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For example, exogenous administration of IL6 in healthy humans in the evening was associated with both fatigue and a sleep disturbing effect in the first half of the night, most likely due to increased secretion of corticotrophinreleasing hormone, ACTH, and cortisol, during the early part of the night, induced by IL6 (144)
References 1.Gkini MA, Kouskoukis AE, Tripsianis G, et al
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Nissl staining was used to determine the loss of Nissl substance and the number of Nissl bodies
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