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Therefore, in this proof-of-concept pilot trial, we hypothesized that treating oxidative stress with NAC before starting taVNS may mitigate oxidative stress and enable taVNS to boost neuroplasticity and enhance motor learning, resulting in improved oral feeding in IDM preparing for a G-tube, compared to our prior cohort of IDMs receiving taVNS alone

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In this context, two distinct clinical trials (NCT00835341 and NCT01695018) investigated the correlation between p16 promoter hypermethylation and OC initiation

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