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A study conducted by the InfantRisk Center (currently under review) found that tirzepatide was either undetectable or barely detectable in breast milk at doses up to 5 mg

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doi: 10.1152/ajpcell.1997.272.1.C59

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The other two routes, 4-hydroxyestrone (4-OHE1) and 16-hydroxyestrone (16-OHE1), produce metabolites that remain more estrogenically active and continue to stimulate estrogen-sensitive tissue [1, 2]

Short-term effects of liraglutide on kidney function and vasoactive hormones in type 2 diabetes: a randomized clinical trial
