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The majority of patients treated with immune checkpoint inhibitors such as monoclonal antibodies suffer from drug-induced immune-related adverse events (irAEs)

The demonstration of increased incidence of culturable bacteria in the mesenteric lymph nodes of patients with intestinal obstruction supports the concept of BT in patients with severe physiologic stress and mucosal injury and would suggest that BT does not take place without mucosal damage and/or inflammation or trauma

JH: Writing original draft, Writing review & editing

doi: 10.1186/s13072-019-0312-7

Vigorous shaking, touching the stopper with bare hands, or improper water use can lead to peptide degradation and inaccurate concentrations, which may result in side effects

They form the bedrock of reproducible, high-integrity science