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Therefore, GSH depletion-induced oxidative stress and cell death depend on the combination of inducer and cell-specific molecular characteristics, i.e

A reduction in the supply of these nutrients, on the other hand, may lead to follicle loss and damage

Since dermal periostin in PN shows no significant correlation with other pruritogenic mediators in the dermis (including IL-31, IL-31R, and OSMR), it might be an independent contributor to pruritus in PN (64)
2016 Jul;60(7):1637-48

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[PubMed: 15578035] 103
