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If female mitochondria accumulate an excess of antioxidant capacity, further elevating GSH might free up excess NADPH to serve as a substrate for NADPH oxidase 2 (NOX2) in the generation of superoxide ions

94 Finally, intestinal damage or inflammation caused by malnutrition can reduce ALP production leading to lower ALP levels

Ann Intern Med 152, 568-77 (2010)

The levels of glutamic acid, aspartic acid, proline, serine, alanine, tyrosine, cysteine, and isoleucine were decreased after LPS administration, which was related to the down-regulation of alanine, aspartate, and glutamate metabolism, arginine and proline metabolism, and cysteine and methionine metabolism

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