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This change involves the substitution of a glutamate residue for the lysine normally found in position 14 of the protein, though the functional implications of this alteration are not yet fully understood

Vertebral compression fracture A compression fracture is a collapse of a vertebra

Numbness or weakness in the arms, legs, and facial muscles

The primary outcome measure being assessed was the change in HbA1c from baseline to the end of treatment at week 32, while seconday outcome measures were related to endpoints of continuous glucose monitoring included time in range and time aboe range [2]

Athauda, D

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