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On April 16, Flint Emergency Manager Ed Kurtz tells the state treasurer that the city is going to join the KWA

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Many pharmaceutical companies have tried to develop drugs that target Mcl-1, but this has been difficult because the interaction between Mcl-1 and its target protein occurs in a long stretch of 20 to 25 amino acids, which is difficult to block with the small molecules typically used as drugs

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[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Sans M., Pans J., Ardite E