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58 59 Nitrous oxide toxicity The Association of British Neurologists has recently issued guidance on recognising and managing nitrous oxide toxicity associated with B 12 deficiency

It should be kept at room temperature, typically between 15C and 30C (59F and 86F), and should not be frozen

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This combination reliably produces better results than either ingredient alone, without stacking irritation

One explanation may be that at least some of the neurological consequences of vitamin B 12 deficiency are irreversible

Health Canada classifies them accordingly, and suppliers operating within Canadian guidelines provide them for non-therapeutic research use