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Description
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Increased TSPO density has been observed during depressive episodes, providing insight into how neuroinflammation may manifest as a mood disorder, thus reinforcing the need for further research on neuroinflammatory biomarkers in a clinical setting [73]

Oxidative stress and inflammation contribute to most human diseases

Interestingly, the consequences of the ROS-induced PCD depend on the context: in some cases, it facilitates pathogen colonization, increasing susceptibility, while in others, it restricts infection, halting pathogen progression and symptom development (Van Breusegem and Dat, 2006

Nitrotyrosine is extremely useful for measuring the formation of peroxynitrite, but this requires additional experimental validation

This failure stands in complete contrast to other members of the OxyR regulon
