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There was a tendency toward higher t 1/2 with increasing hepatic impairment ranging from 174 h (range 144204 h) in the group with normal hepatic function to 199 h (range 184214 h) in the group with severe hepatic impairment

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10.1001/jama.2008.864 30 LuZ.PuC.ZhangY.SunY.LiaoY.KangZ.et al (2022)