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Additional regulatory mechanisms include SRC-2mediated reductive carboxylation, compensatory glutamine addiction induced by PDHA1 loss, Guanine Monophosphate Synthetase(GMPS) driven purine biosynthesis, reciprocal regulation between GLS and CAD, epigenetic modulation via MeCP2/DNMT, and C5a complement signaling that promotes glutamine consumption in castration-resistant prostate cancer (4143)

Blood Cells Mol Dis 47: 176181, 2011 [DOI] [PubMed] [Google Scholar] 49.Kuroda J, Ago T, Matsushima S, Zhai P, Schneider MD, Sadoshima J

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10.1016/j.celrep.2017.05.077 64 ServilloL.D'OnofrioN.GiovaneA.CasaleR.CautelaD.CastaldoD.et al (2018)

Data availability The datasets generated during and analyzed during the current study are available from the corresponding author on reasonable request