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It becomes more of a safety problem when the pill is several years past the date, has been stored in heat or humidity, or came from a source you cant verify

[14] There is not enough data to guarantee safety for the fetus or nursing infant

AOD 9604 went down this path for a specific indicationobesitybut did not complete it successfully to gain approval

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Lyophilization helps preserve peptide stability during storage and allows researchers to reconstitute the material for controlled laboratory experimentation