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[PubMed: 11327370] 33

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99,100 Other techniques have been applied for the removal of cNFs, including electrodessication and radiofrequency ablation

Benefits were dose related and lasted up to 4 hours, although they began to fade after 2 hours

The non-enzymatic succinylation is mainly mediated by intracellular succinyl-CoA which can be modulated by succinyl-CoA metabolism-targeting enzymes, such as OXCT1, a member of the CoA transferase family I [49], and SUCLA2/SUCLG2, the ADP-forming succinyl-CoA synthetase [32, 50]

The best route depends on the patient, the type of neurologic involvement, severity of illness, diagnostic findings, treatment history, and risks of therapy