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Epitalon (also known as Epithalon) is a synthetic tetrapeptide, echoing the natural polypeptide Epithalamin extracted from the pineal gland

doi: 10.6061/clinics/2018/e473s 2 PizzinoGIrreraNCucinottaMPallioGManninoFArcoraciVet al

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Its effect was associated with a significant decrease in oxidative stress parameters and likely maintained NO system function, providing that BPC 157 interacted with eNOS and COX2 gene expression, in a particular way and counteracted the noxious effect of the NOS-blocker, L-NAME

Endothelial cells, which line the inside of blood vessels, play a key role in regulating blood pressure, blood flow, and clotting and they too appear to be positively affected by MOTS-c

Biomed Res Int 2019(1):9732325