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Metal ions coordination-driven composite systems enabled stable delivery of specific drugs in response to physiological conditions

Hydrogen is a safe, economically feasible adjunctive therapy that preclinical evidence suggests may benefit problematic wound healing through its multifaceted mechanisms

Succinyl-CoA allosterically inhibits HMGCS2 and it also serves as a substrate for succinylation of lysine residues in the enzyme

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Take-home message For the purpose of evaluating anti-aging treatments, the ideal biological clock should be created with these two techniques: It should be trained on historic samples where mortality data is available, rather than current samples where all we know is chronological age, and Components should be chosen by hand to assure all are upstream causes of aging rather than downstream responses to damage

doi: 10.1002/jmv.25728 73 LiewP