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Results Lack of TrkB signalling in iSPNs increases striatal DA The cause of the DA dysfunction in patients with HD and in rodent models is currently unclear

This mechanism plays a role in activating various downstream pathways, including RAS/MAPK, PI3K/AKT, Wnt/-catenin, and JAK/STAT, which are crucial for controlling a range of cellular physiological activities such as differentiation, proliferation, epithelial cell movement, angiogenesis, and EMT [21]

L.VacaC

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Here, we examine the otoprotective effects of Dihexa in a zebrafish model of chemical ototoxicity

This demonstrated that GYY4137 can mitigate LPS/ATP-induced inflammatory responses by inhibiting the activation of NF-B signaling pathway