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J Hepatol (2014) 61:136575

doi: 10.2147/IJN.S207666 52 KuaiXZhuYYuanZWangSLinLYeXet al

191 The resistance of gastric cancer to chemotherapy agents like 5-FU limits their clinical application, and the regulation of ferroptosis is closely related to gastric cancer progression and chemotherapy resistance

& Pahr, S
HillASullivanAChalmersJDe SoyzaAElbornSFlotoAet al

The levels of histamine secreted by mast cells from Trx1-Tg mice were significantly reduced compared with that in WT mice, and the levels of intracellular ROS suggested that Trx1 inhibits mast cell degranulation by blocking ROS production (94, 96), whereas Trx1 effectively inhibits PLC, PKC, and Ca2+ influx in the signal transmission of ROS-activated FcRI-dependent mast cells ( Figure 1C )
