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High levels of body fat especially visceral fat surrounding internal organs increase the likelihood of insulin resistance and type 2 diabetes and contribute to hypertension, high cholesterol and an increased risk of cardiovascular diseases such as heart attack and stroke

Most people with PKD are adults
Retatrutide also showed potential cardiovascular benefits

Mild-to-moderate non-alcoholic fatty liver disease (NAFLD) is not a contraindication to GLP-1 weight loss injections, and these medications may actually improve liver health by reducing hepatic fat accumulation
Multiple drugs targeting GLP-1 functions, ER UPR, bile acid signaling, and the microbiota have already proven to be effective in the treatment of T2D and IBD (Figure 6)

Frequently Asked Questions About Medical Weight Loss Coral Springs What is medical weight loss and how does it work