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Abnormal IGF-1 and GH levels have been proposed to play a key role in obesity [130, 240, 241]

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336 In addition, miR-145 regulates the expression of the drug resistance gene MDR1, thereby improving drug sensitivity to 5-aminosalicylic acid and glucocorticoids in the treatment of UC

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It has demonstrated strong analgesic activities in various animal models of pain, including those simulating inflammatory and neuropathic conditions [194,195,196]

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Nerves use a lot of energy, but they cant store it so they need a constant supply

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