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In conclusion, previous findings suggested that CS concentration of 4 mg%, (F4) yielded the most promising quality attributes regarding the size (312 2.18 nm), homogeneity (PDI 0.419 0.03) surface charge (34 2.01 mv), and the highest EE% 81.9 1.90% Therefore, F4 is used for further investigations

Hesperidin protects against cisplatin-induced cardiotoxicity in mice by regulating the p62-Keap1-Nrf2 pathway

27,28 Notably, impairment of the unfolded protein response (UPR), including XBP1 or IRE1 deficiency, has also been implicated in -cell transdifferentiation or dedifferentiation

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