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These are mediated by 11-hydroxylase (P450c11 or CYP11B1), which generates cortisol (followed by activities of the ER enzymes P450c21 and P450c17), and aldosterone synthase (P450c11AS or CYP11B2) which produces aldosterone 91,92,93,94

The aim of this study was to review the most important reports related to the role of glutathione S-transferases in the pathophysiology of two of the most common diseases in modern society cancers and cardiovascular diseases

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However, integrating or predicting these relationships using AI-based approaches may open new avenues for elucidating previously unknown physiological and phenotypic aspects

[DOI] [PubMed] [Google Scholar] 66.Marnett LJ, Riggins JN, West JD

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