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Epothilone is one of the lead anticancer compounds, with unique binding affinity to the cellular -tubulin, however, the solubility and efficiency towards the drug-resistant tumors are the challenges

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Results OA-NPs@OA exhibited significantly enhanced cellular uptake via CD44 receptor-mediated endocytosis in keratinocytes, achieving a markedly lower IC50 value compared to free OA and considerably stronger apoptosis induction effects

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