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[DOI] [PubMed] [Google Scholar] 46.Rothkrantz-Kos S, Drent M, Vuil H, et al

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The APAP group showed a significant decrease in SIRT-1 expression level compared to the control group

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Oxidative stress arises when there is an imbalance between oxidant generation and antioxidant capacity, leading to the accumulation of reactive oxygen species (ROS) and reactive nitrogen species (RNS), ultimately resulting in cellular injury and dysfunction 1
