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Recent studies indicate that the biochemical and pharmacological properties of coumarins depend on their substitution patterns, which influence therapeutic applications and can positively affect toxicity

Riluzole was the first FDA-approved compound for ALS (in 1995), which inhibits glutamatergic neurotransmission and thus inhibits excitotoxicity (Dharmadasa and Kiernan, 2018

Your body does not naturally produce B12, which can lead some individuals to become deficient, and in some cases, anemic

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Doll et al., 2017)