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ROS are produced by the interaction between Fe 2+ and NADPH oxidase during ferroptosis

Prior research has highlighted the therapeutic potential of DAPA in managing DM and its complications

Scandinavian Journal of Gastroenterology 1999

Glutathione is a naturally occurring tripeptide compound composed of glutamine, cysteine, and glycine

Balskus EP Discovery of the Azaserine Biosynthetic Pathway Uncovers a Biological Route for A-Diazoester Production

The advent of targeted therapies directed against key cytokines involved in the different cell death pathways highlights the clinical importance of identifying the leading pathways to guide treatment choices: Patients whose phenotype is driven by TNF-alpha-induced necroptotic cell death may benefit from TNFi, and interleukin-1 inhibitors have markedly improved the outcome of patients with autoinflammatory diseases driven by increased pyroptosis [23, 25]