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Congressional passage of the Indian Removal Act of 1830, which fulfilled the Compact of 1802, was related to that gold discovery and the desire of Whites to settle the land, as well as President Andrew Jackson's commitment to removal of Native Americans to enable development by the whites

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Human-equivalent doses (HEDs) were estimated using standard allometric scaling [HED (mg/kg) = animal dose (mg/kg) Km_animal/Km_human

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