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In the liver, the rate of synthesis of selected proteins (i.e., albumin, transferrin, prealbumin, retinol-binding protein, and fibronectin) is decreased, whereas acute phase protein synthesis is accelerated [94]

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Also, in clinical pharmacokinetic studies and case reports, the administered SJW products were often lacking sufficient specifications (herbal drug substance or extract, drugextract ratio, solvent), especially regarding the hyperforin content

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