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However, ROS can also inhibit the activation of Akt by oxidizing Cys-residues in the active center

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Many markers of oxidative stress, such as lipid peroxide (LOOH) (77), malondialdehyde (MDA) (78), a marker of oxidative DNA damage 8-hydroxy-2'-deoxyguanosine (8-OH-dG) (79), and 3-nitrotyrosine (3-NT), are elevated in children with ASD

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