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These acylcarnitines can be exported from the mitochondria and cell, preventing the toxic accumulation of acyl-CoA intermediates that inhibit key metabolic enzymes

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The dual character is critical for the formation of the lipid bilayer

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Several microbially derived metabolites have been associated with elevated CVD risk, including phenylacetylglutamine (20), imidazole propionate (21), and trimethylamine (TMA) (10, 22)