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Niacinamide: brightening vitamin B3 that helps reduce dark spots by inhibiting pigment formation, whilst infusing a characteristic glow into skin

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As a result, it increases the activity of the N-acetyltransferase enzyme, which is a rate-limiting enzyme in melatonin synthesis in increasing intracellular cAMP and melatonin synthesis increases from serotonin [30, 32]

Genetic alterations in oxidant and Anti-Oxidant enzymes in the vascular system
(2005) Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
