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In this section, we provide the proposed payment methodology, and a summary of the comments we received as well as our responses

Lipolysis Enhancement and Lipogenesis Inhibition In obese Zucker rats, daily oral administration of AOD9604 significantly increased lipolytic activity in adipose tissue compared to controls, establishing direct adipocyte-level lipolysis stimulation as a key mechanism of action in pre-clinical models

Public Reporting Reminder In the CY 2022 HH PPS final rule (86 FR 62332 through 62333), we proposed that we will publicly report the following information for the expanded HHVBP Model: Applicable measure benchmarks and achievement thresholds for each small- and large-volume cohort