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DOI: Ryu HW, Lee DH, Won HR, Kim KH, Seong YJ, Kwon SH

10.1016/j.pneurobio.2019.101729

Astrocytes and brain-derived neurotrophic factor (BDNF)

It's considered to be the "master antioxidant." It is the primary detoxifier and anti-inflammatory agent in every body cell

These patterns are consistently observed in diverse mouse models, including wild type and transgenic mice across various strains, as highlighted in a review by Wood and Zuo (27)

The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal