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Loss of DOT1L caused a decrease in H3K9me2, resulting in decreased transcription of genes expressed in upper-layer neurons (Satb2, Pou3f3, Cux2, and the Sox family)

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Polygonum multiflorum root extract as a potential candidate for treatment of early graying hair

Many promising results support further research with rapamycin as a potential intervention for common neurodegenerative diseases associated with aging, including Alzheimers disease and Parkinsons disease [48, 49]

In parallel, we scrutinized the anti-neuroinflammatory effects of both standard compounds and UDE by examining their impact on the downregulation of proinflammatory cytokines in LPS-stimulated BV-2 cells

Therefore, in previous reports, the prognosis of these two types was examined collectively, and age, tumor diameter, and the number of vascular invasions were cited as risk factors for recurrence [141, 143-145]